Which of the following symptoms is most commonly associated with monkeypox?

A) High fever

B) Severe headaches

C) Rash that progresses from macules to vesicles

D) All of the above

Answer: D) All of the above

Explanation: Monkeypox can present with a range of symptoms, including fever, severe headaches, and a distinctive rash that evolves through stages from macules to vesicles and pustules. Therefore, all of the symptoms listed are commonly associated with the infection.